Cellulase is a type of glycoside hydrolase capable of hydrolyzing cellulose. It can be classified into two major categories based on its preferred pH range: acid cellulase and neutral cellulase. Acid cellulase has an optimum pH range of 3.0 to 5.0, making it suitable for catalytic activity under mildly acidic conditions. On the other hand, neutral cellulase has an optimum pH range of 6.0 to 8.0, allowing it to exhibit enzymatic activity under neutral conditions. Both types of enzyme cellulase share a similar optimum temperature range, typically between 45-55° C. They secrete various subtypes of cellulase, which cleave glycosidic bonds within cellulose molecular chains, generating oligosaccharides and other products. Both classes of cellulase require specific metal ions, such as Mn2+ and Zn2+, as cofactors to activate their enzymatic activity. Cellulase plays a crucial role in various industrial and biotechnological applications, facilitating cellulose degradation and promoting the efficient utilization of resources.